Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
| ▸ | CASP5 | P51878 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210238 | 1.00 | ALOX5 (0.38) | ALOX5CASP1CASP4CASP5PTGS1 | |
| SCHEMBL8598222 | 0.87 | ALOX5 (0.47) | ALOX5CASP1CASP4CASP5PTGS1 | |
| SCHEMBL9201759 | 0.85 | ALOX5 (0.36) | ALOX5CASP1CASP4CASP5PTGS1 | |
| SCHEMBL9201751 | 0.85 | ALOX5 (0.36) | ALOX5CASP1CASP4CASP5PTGS1 | |
| Hydrochloric Acid SCHEMBL9203276 | 0.84 | ALOX5 (0.36) | ALOX5CASP1CASP4CASP5PTGS1 | |
| Hydrochloric Acid SCHEMBL9203281 | 0.84 | ALOX5 (0.36) | ALOX5CASP1CASP4CASP5PTGS1 | |
| SCHEMBL9203503 | 0.83 | ALOX5 (0.44) | ALOX5CASP1CASP4CASP5PTGS1 | |
| Hydrochloric Acid SCHEMBL9208686 | 0.81 | ALOX5 (0.37) | ALOX5CASP1CASP4CASP5 | |
| Hydrochloric Acid SCHEMBL9208692 | 0.81 | ALOX5 (0.37) | ALOX5CASP1CASP4CASP5 | |
| SCHEMBL6885035 | 0.81 | TSHR (0.39) | ALOX5CASP1CASP4CASP5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413668-B1 | New 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofuranes 2-(RS)-substitutes, useful as antioxidizing pharmaceutical products having mucoregolating and anti-ischemic properties | FOSCAMA BIOMED CHIM FARMA (IT) | 1995-12-06 | — | — | EP | disclosed |
| US-5114966-A | Radical scavengers | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1992-05-19 | — | — | US | disclosed |
| EP-0413668-A2 | New 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofuranes 2-(RS)-substitutes, useful as antioxidizing pharmaceutical products having mucoregolating and anti-ischemic properties | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-02-20 | — | — | EP | disclosed |