Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210568 | 1.00 | CYP1A2 (0.63) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL11231490 | 0.81 | LMNA (0.68) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL11231495 | 0.81 | LMNA (0.68) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL13810256 | 0.81 | MEN1 (0.58) | CYP1A2CYP2C9HPGDALDH1A1GAA | |
| SCHEMBL3681187 | 0.77 | MEN1 (0.68) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL3681189 | 0.77 | MEN1 (0.68) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL7636680 | 0.77 | TDP1 (0.52) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL7636678 | 0.77 | TDP1 (0.52) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL10944453 | 0.75 | GLA (0.53) | CYP1A2CYP2C9HPGDLMNAALDH1A1 | |
| SCHEMBL10944462 | 0.75 | GLA (0.53) | CYP1A2CYP2C9HPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7017912-A | — | — | None | — | — | JP | disclosed |
| JP-H0717912-A | CINNAMYLIDIENEMALONATE DERIVATIVE, ULTRAVIOLET RAYS ABSORBER AND SKIN EXTERNAL PREPARATION CONTAINING THE SAME BLENDED THEREIN | SHISEIDO CO LTD | 1995-01-20 | — | — | JP | disclosed |