Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.57 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536511 | 0.93 | AGTR1 (0.67) | AGTR1ABCC3ABCC2AGTR2 | |
| SCHEMBL9208575 | 0.86 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL8954159 | 0.85 | AGTR1 (0.61) | AGTR1ABCC3ABCC2AGTR2 | |
| SCHEMBL9203998 | 0.80 | AGTR1 (0.75) | AGTR1 | |
| SCHEMBL9210589 | 0.80 | AGTR1 (0.75) | AGTR1 | |
| SCHEMBL9213511 | 0.80 | AGTR1 (0.75) | AGTR1 | |
| SCHEMBL8534004 | 0.79 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL8957152 | 0.76 | AGTR1 (0.61) | AGTR1 | |
| SCHEMBL8439336 | 0.75 | AGTR1 (0.48) | AGTR1ABCC3ABCC2AGTR2 | |
| SCHEMBL9206267 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | disclosed |