Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.55 |
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | ACHE | P22303 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9217447 | 0.99 | MAOB (0.57) | MAOBMAOAACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9213168 | 0.99 | MAOB (0.57) | MAOBMAOAACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9211581 | 0.99 | MAOB (0.57) | MAOBMAOAACHEKDM4EALDH1A1 | |
| SCHEMBL9218485 | 0.88 | ALDH1A1 (0.54) | MAOBMAOAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9220668 | 0.87 | ALDH1A1 (0.53) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL7295219 | 0.85 | MAOB (0.62) | MAOBMAOAACHEKDM4EALDH1A1 | |
| SCHEMBL11096505 | 0.84 | MAOB (0.63) | MAOBMAOAACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9219927 | 0.83 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL9218684 | 0.82 | SLC6A4 (0.44) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL9216988 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | claimed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | claimed |
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |