Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | NGFR | P08138 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079008 | 0.96 | FTO (0.45) | FTONTRK1NGFRPABPC1MEN1 | |
| SCHEMBL9218810 | 0.89 | FTO (0.48) | FTONTRK1NGFRPABPC1MEN1 | |
| Bisnafide SCHEMBL29617562 | 0.87 | FTO (0.61) | FTONTRK1NGFRPABPC1MEN1 | |
| Bisnafide SCHEMBL9136683 | 0.87 | FTO (0.61) | FTONTRK1NGFRPABPC1MEN1 | |
| Bisnafide SCHEMBL9136305 | 0.87 | FTO (0.61) | FTONTRK1NGFRPABPC1MEN1 | |
| Bisnafide SCHEMBL9135739 | 0.87 | FTO (0.61) | FTONTRK1NGFRPABPC1MEN1 | |
| Bisnafide SCHEMBL9135370 | 0.87 | FTO (0.61) | FTONTRK1NGFRPABPC1MEN1 | |
| SCHEMBL9238619 | 0.86 | FTO (0.60) | FTONTRK1NGFRPABPC1MEN1 | |
| SCHEMBL9352511 | 0.86 | FTO (0.60) | FTONTRK1NGFRPABPC1MEN1 | |
| SCHEMBL9348633 | 0.86 | FTO (0.60) | FTONTRK1NGFRPABPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |