Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 2/20 | 0.33 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | ADH1A | P07327 | 2/20 | 0.33 |
| ▸ | ADH4 | P08319 | 2/20 | 0.33 |
| ▸ | ADH7 | P40394 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340146 | 0.93 | TSHR (0.57) | TSHRALDH1A1KDM4EPLA2G2CEPHX1 | |
| SCHEMBL9206049 | 0.90 | TSHR (0.47) | TSHRALDH1A1KDM4EPLA2G2CLMNA | |
| SCHEMBL9541689 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B | |
| SCHEMBL27800763 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B | |
| SCHEMBL9208917 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B | |
| SCHEMBL24353239 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B | |
| SCHEMBL9206251 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B | |
| SCHEMBL11699658 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B | |
| SCHEMBL9204346 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B | |
| SCHEMBL14625028 | 0.86 | EPHX1 (0.48) | TSHRALDH1A1KDM4EEPHX1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |