Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5086835 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL5091622 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL5086699 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL5088583 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL10486476 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL5088372 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL5087655 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL1011394 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Bromide SCHEMBL5085114 | 0.98 | FDPS (0.37) | FDPSLMNADNM1OPRM1 | |
| SCHEMBL22367822 | 0.98 | FDPS (0.41) | FDPSLMNADNM1OPRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11188002-B2 | Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2021-11-30 | — | — | US | disclosed |
| CN-108885415-B | Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, image forming apparatus, and dispersant for fluorine-based resin | 三菱化学株式会社 | 2021-11-09 | — | — | CN | disclosed |
| CN-107428922-B | Electrophotographic photoreceptor and image forming apparatus | 三菱化学株式会社 | 2021-06-01 | — | — | CN | disclosed |
| US-10725391-B2 | Electrophotographic photoreceptor and image forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2020-07-28 | — | — | US | disclosed |
| US-20200233322-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2020-07-23 | — | — | US | disclosed |
| US-20190033734-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, IMAGE FORMING APPARATUS, AND DISPERSANT FOR FLUORORESIN | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-01-31 | — | — | US | disclosed |
| US-10185237-B2 | Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, image forming apparatus, and polyarylate resin | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-01-22 | — | — | US | disclosed |
| EP-2687907-B1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND RESIN COMPOSITION | IDEMITSU KOSAN CO (JP) | 2018-02-14 | — | — | EP | disclosed |
| US-20180011412-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-01-11 | — | — | US | disclosed |
| US-9494883-B2 | Electrophotographic photoreceptor and resin composition | IDEMITSU KOSAN CO., LTD. (JP) | 2016-11-15 | — | — | US | disclosed |
| EP-1124879-A1 | WEATHERABLE BLOCK COPOLYESTERCARBONATES, METHODS FOR THEIR PREPARATION AND BLENDS CONTAINING THEM | GENERAL ELECTRIC COMPANY (US) | 2001-08-22 | — | — | EP | disclosed |
| US-6265522-B1 | RESORCINOL ACRYLATE POLYESTER | GENERAL ELECTRIC COMPANY | 2001-07-24 | — | — | US | disclosed |
| WO-2000069945-A1 | THERMALLY STABLE POLYMERS, METHOD OF PREPARATION, AND ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000026275-A1 | WEATHERABLE BLOCK COPOLYESTERCARBONATES, METHODS FOR THEIR PREPARATION AND BLENDS CONTAINING THEM | GENERAL ELECTRIC COMPANY (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0050821-B1 | HEAT-RESISTING AROMATIC POLYESTER RESIN AND PROCESS FOR PREPARING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-07-23 | — | — | EP | disclosed |
| EP-0056149-B1 | PROCESS FOR MANUFACTURING AROMATIC POLYESTERS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-06-11 | — | — | EP | disclosed |
| EP-0058938-B1 | POLYESTERAMIDE AND PROCESS FOR PREPARING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-01-29 | — | — | EP | disclosed |
| US-4474936-A | HEAT AND HYDROLYSIS RESISTANCE, DIELECTRIC | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-10-02 | — | — | US | disclosed |
| US-4426511-A | Heat-resisting aromatic polyester resin and process for preparing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-01-17 | — | — | US | disclosed |
| US-4412057-A | Process for manufacturing aromatic polyesters | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-25 | — | — | US | disclosed |