Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211548 | 1.00 | FAAH (0.37) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9206191 | 0.93 | FAAH (0.39) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9211476 | 0.93 | FAAH (0.39) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9211480 | 0.93 | FAAH (0.39) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9206186 | 0.93 | FAAH (0.39) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9211879 | 0.91 | FAAH (0.36) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9211885 | 0.91 | FAAH (0.36) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9204299 | 0.89 | FAAH (0.44) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9204294 | 0.89 | FAAH (0.44) | FAAHTRPV1LPAR2LPAR3FFAR1 | |
| SCHEMBL9206255 | 0.86 | FAAH (0.44) | FAAHTRPV1LPAR2LPAR3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |