Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH4 | P08319 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087395 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL5613172 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL1971599 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL5090277 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL5090691 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL5613428 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL5086519 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL5613268 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL5613655 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL1019949 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |