Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | SDHA | P31040 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CALML3 | P27482 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213579 | 0.85 | MAOB (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL27951203 | 0.85 | F10 (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6097066 | 0.85 | F10 (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9029466 | 0.85 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8788012 | 0.84 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL19250587 | 0.84 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| Hydrochloric Acid SCHEMBL8695876 | 0.84 | MAOA (0.54) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8789075 | 0.84 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9550276 | 0.83 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9550299 | 0.83 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |