Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514634 | 0.97 | KMT2A (0.43) | RAB9AMEN1NPC1KMT2A | |
| Toluene SCHEMBL7509310 | 0.92 | MEN1 (0.47) | RAB9AMEN1NPC1KMT2A | |
| SCHEMBL9264803 | 0.84 | KMT2A (0.43) | RAB9AMEN1NPC1KMT2A | |
| SCHEMBL7511540 | 0.82 | KMT2A (0.45) | MEN1KMT2A | |
| SCHEMBL9212241 | 0.82 | MEN1 (0.46) | RAB9AMEN1NPC1KMT2A | |
| SCHEMBL4048240 | 0.81 | KMT2A (0.46) | MEN1KMT2A | |
| SCHEMBL7507722 | 0.80 | PKM (0.68) | KMT2A | |
| SCHEMBL4408005 | 0.76 | TRPV1 (0.42) | KMT2A | |
| SCHEMBL4412199 | 0.76 | TRPV1 (0.42) | KMT2A | |
| SCHEMBL4405063 | 0.76 | TRPV1 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684945-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |