Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.61 |
| ▸ | TACR3 | P29371 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485370 | 0.91 | TACR1 (0.61) | TACR1TACR3MEN1KMT2A | |
| SCHEMBL9274807 | 0.91 | TACR1 (0.61) | TACR1TACR3MEN1KMT2A | |
| SCHEMBL8198646 | 0.82 | TACR1 (0.77) | TACR1TACR3 | |
| SCHEMBL8198649 | 0.82 | TACR1 (0.77) | TACR1TACR3 | |
| SCHEMBL1388670 | 0.79 | TACR1 (0.64) | TACR1TACR3 | |
| SCHEMBL9541550 | 0.79 | TACR1 (0.43) | TACR1TACR3MAPT | |
| SCHEMBL9373898 | 0.79 | TACR1 (0.51) | TACR1TACR3MEN1MAPTKMT2A | |
| SCHEMBL7856733 | 0.78 | MAPT (0.64) | TACR1NPC1POLBRAB9ACDK4 | |
| SCHEMBL8488187 | 0.78 | NMBR (0.50) | TACR1MEN1KMT2A | |
| SCHEMBL6888854 | 0.78 | TACR1 (0.46) | TACR1TACR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |