Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NMBR | P28336 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888854 | 0.86 | TACR1 (0.46) | TACR1TACR3ACE | |
| SCHEMBL8485370 | 0.82 | TACR1 (0.61) | TACR1TACR3 | |
| SCHEMBL9274807 | 0.82 | TACR1 (0.61) | TACR1TACR3 | |
| SCHEMBL6888466 | 0.81 | USP2 (0.47) | TACR1KDM4EALDH1A1ACECYP3A4 | |
| SCHEMBL7672110 | 0.81 | TACR1 (0.54) | TACR1TACR3NMBR | |
| SCHEMBL8488187 | 0.79 | NMBR (0.50) | TACR1KDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9212280 | 0.79 | TACR1 (0.61) | TACR1TACR3MAPT | |
| SCHEMBL9373898 | 0.77 | TACR1 (0.51) | TACR1TACR3KDM4EALDH1A1ACE | |
| SCHEMBL9528893 | 0.77 | TACR1 (0.47) | TACR1TACR3ACECYP2D6MAPT | |
| SCHEMBL9336196 | 0.76 | KMT2A (0.47) | KDM4EALDH1A1ACECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |