Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | RECQL | P46063 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212306 | 1.00 | EGFR (0.65) | EGFRERBB2DNM1ALDH1A1MAPT | |
| SCHEMBL9216287 | 0.86 | MEN1 (0.67) | EGFRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9216292 | 0.86 | MEN1 (0.67) | EGFRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2201000 | 0.84 | MCL1 (0.60) | EGFRALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL9346949 | 0.83 | DNM1 (0.79) | EGFRERBB2DNM1ALDH1A1MAPT | |
| SCHEMBL9216392 | 0.83 | DNM1 (0.79) | EGFRERBB2DNM1ALDH1A1MAPT | |
| SCHEMBL9216404 | 0.82 | EGFR (0.56) | EGFRERBB2DNM1ALDH1A1MAPT | |
| SCHEMBL9216389 | 0.82 | EGFR (0.56) | EGFRERBB2DNM1ALDH1A1MAPT | |
| SCHEMBL9347097 | 0.80 | DNM1 (0.72) | EGFRERBB2DNM1ALDH1A1MAPT | |
| SCHEMBL9347102 | 0.80 | DNM1 (0.72) | EGFRERBB2DNM1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475214-B1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5326785-A | Arteriosclerosis andn diseases of the circulatory system | SUNTORY LIMITED (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5232941-A | Therapeutic agents for diseases of the circulatory system | SUNTORY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0475214-A1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |