Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562415 | 1.00 | CYP2C9 (0.40) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL7519192 | 0.90 | MEN1 (0.40) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL7519196 | 0.90 | MEN1 (0.40) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL9561731 | 0.88 | MEN1 (0.40) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL4567521 | 0.88 | MEN1 (0.40) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL3695378 | 0.88 | MEN1 (0.40) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL30843044 | 0.88 | MEN1 (0.40) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL9486031 | 0.86 | CYP11B1 (0.36) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL9486024 | 0.86 | CYP11B1 (0.36) | CYP2C9CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL4887115 | 0.85 | CES2 (0.49) | CYP2C9CYP11B1CYP11B2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457090-B1 | Process for the preparation of 3-amino-2 (het)aroyl-acrylic acid derivatives | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5182401-A | Bactericide intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-26 | — | — | US | disclosed |
| EP-0457090-A2 | Process for the preparation of 3-amino-2 (het)aroyl-acrylic acid derivatives | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |