Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216793 | 0.93 | POLB (0.58) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9430659 | 0.92 | POLB (0.60) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9221106 | 0.92 | POLB (0.60) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9218097 | 0.88 | ALDH1A1 (0.62) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9219757 | 0.88 | TP53 (0.63) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9218489 | 0.86 | POLB (0.64) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9430330 | 0.86 | SMN1; SMN2 (0.51) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9431339 | 0.86 | POLB (0.66) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9683402 | 0.86 | ALDH1A1 (0.56) | TP53HPGDKDM4ELMNATSHR | |
| SCHEMBL9219577 | 0.85 | ALDH1A1 (0.52) | TP53HPGDKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |