Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205454 | 1.00 | CA2 (0.55) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL9213269 | 1.00 | CA2 (0.55) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL29444757 | 0.83 | CA2 (0.51) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL17272731 | 0.83 | CA2 (0.51) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL1043944 | 0.83 | CA2 (0.51) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL1043824 | 0.83 | CA2 (0.51) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL17150883 | 0.83 | CA2 (0.51) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL17272730 | 0.83 | CA2 (0.51) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL29481769 | 0.83 | CA2 (0.51) | CA2DRD2ALOX5LTA4HFFAR1 | |
| SCHEMBL21198157 | 0.81 | CHRNB4 (0.47) | CA2DRD2HTR1AADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0520674-A1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |