Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179840 | 0.74 | TLR4 (0.42) | HTR2A | |
| SCHEMBL10975419 | 0.74 | — | — | |
| SCHEMBL39899 | 0.70 | MAPT (0.44) | — | |
| SCHEMBL11181948 | 0.69 | TLR4 (0.47) | — | |
| SCHEMBL274509 | 0.67 | DRD2 (0.51) | — | |
| SCHEMBL5201714 | 0.67 | TLR4 (0.55) | — | |
| SCHEMBL9924735 | 0.67 | TLR4 (0.42) | — | |
| SCHEMBL5684775 | 0.65 | TLR4 (0.47) | — | |
| SCHEMBL296381 | 0.65 | TLR4 (0.35) | — | |
| SCHEMBL14112201 | 0.64 | TLR4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375210-B1 | Pyrazoloisoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LTD (GB) | 1995-05-03 | — | — | EP | disclosed |
| US-4963558-A | NEUROLEPIC AGENT, SEDATIVES | LILLY INDUSTRIES LIMITED (GB) | 1990-10-16 | — | — | US | disclosed |
| EP-0375210-A1 | Pyrazoloisoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |