Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 4/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575565 | 0.85 | CHRM2 (0.52) | CHRM2MC4RMC5RACHEAMY1A | |
| SCHEMBL19226117 | 0.78 | CHRM2 (0.37) | CHRM2HRH3MC4RMC5RACHE | |
| SCHEMBL55096 | 0.77 | DAO (0.38) | ACHEHTTALDH1A1LMNA | |
| SCHEMBL26230987 | 0.77 | CHRM2 (0.44) | CHRM2MC4RMC5RAMY1AALDH1A1 | |
| SCHEMBL10864363 | 0.77 | CHRM2 (0.73) | CHRM2MC4RMC5RAMY1AHTT | |
| SCHEMBL9216895 | 0.76 | PRMT6 (0.53) | CHRM2ACHEPRMT6 | |
| SCHEMBL10864344 | 0.74 | CHRM2 (0.42) | CHRM2MC4RMC5RAMY1AALDH1A1 | |
| SCHEMBL10863545 | 0.74 | CHRM2 (0.46) | CHRM2MC4RMC5RAMY1AUSP2 | |
| SCHEMBL9211900 | 0.73 | PRMT6 (0.50) | CHRM2ACHEPRMT6 | |
| SCHEMBL10862582 | 0.73 | CHRM2 (0.44) | CHRM2MC4RMC5RAMY1AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413343-B1 | Furan derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |