Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9739777 | 0.98 | MAPK1 (0.32) | MAPK1MEN1POLBKMT2ANOS2 | |
| SCHEMBL9212354 | 0.87 | HRH3 (0.35) | HRH3 | |
| Hydrochloric Acid SCHEMBL9741088 | 0.87 | HRH3 (0.34) | HRH3 | |
| SCHEMBL9206942 | 0.83 | KDM4E (0.35) | MAPK1MEN1POLBKMT2ANOS2 | |
| Hydrochloric Acid SCHEMBL9740720 | 0.82 | KDM4E (0.34) | MAPK1MEN1POLBKMT2ANOS2 | |
| SCHEMBL9216605 | 0.80 | HRH3 (0.37) | MAPK1MEN1POLBKMT2ANOS2 | |
| Hydrochloric Acid SCHEMBL9739030 | 0.78 | HRH3 (0.38) | MAPK1MEN1POLBKMT2ANOS2 | |
| SCHEMBL9214421 | 0.78 | HRH3 (0.40) | MAPK1MEN1POLBKMT2ANOS2 | |
| Hydrochloric Acid SCHEMBL9208307 | 0.77 | HRH3 (0.39) | MAPK1MEN1POLBKMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL9215780 | 0.75 | DRD2 (0.40) | MAPK1MEN1POLBKMT2ANOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |