Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212620 | 1.00 | AR (0.60) | ARSRD5A2KCNH2 | |
| SCHEMBL5213364 | 0.93 | AR (0.64) | ARSRD5A2KCNH2 | |
| SCHEMBL5213351 | 0.93 | AR (0.64) | ARSRD5A2KCNH2 | |
| SCHEMBL9209700 | 0.92 | AR (0.58) | ARSRD5A2KCNH2 | |
| SCHEMBL9209691 | 0.92 | AR (0.58) | ARSRD5A2KCNH2 | |
| SCHEMBL10631413 | 0.90 | AR (0.62) | ARSRD5A2 | |
| SCHEMBL7623411 | 0.90 | AR (0.62) | ARSRD5A2 | |
| SCHEMBL11005799 | 0.86 | AR (0.68) | ARSRD5A2KCNH2 | |
| SCHEMBL11005803 | 0.86 | AR (0.68) | ARSRD5A2KCNH2 | |
| SCHEMBL8077641 | 0.85 | AR (0.61) | ARSRD5A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468012-B1 | 17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1995-09-20 | — | — | EP | claimed |
| EP-0468012-A1 | 17-g(b)-SUBSTITUTED-4-AZA-5-g(a)-ANDROSTAN-3-ONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1992-01-29 | — | — | EP | claimed |
| EP-0468012-B1 | 17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1995-09-20 | — | — | EP | disclosed |
| US-5155107-A | Inhibiting androgen action, anticarcinogenic agents, treating skin disorders, baldness | FARMITALIA CARLO ERBA (IT) | 1992-10-13 | — | — | US | disclosed |