Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598243 | 0.95 | HTR3A (0.61) | HTR3A | |
| SCHEMBL7655663 | 0.88 | — | — | |
| SCHEMBL10922792 | 0.88 | — | — | |
| SCHEMBL7432371 | 0.86 | HTR3A (0.74) | HTR3A | |
| SCHEMBL10926483 | 0.85 | — | — | |
| SCHEMBL10919444 | 0.84 | — | — | |
| SCHEMBL17417624 | 0.84 | HTR3A (0.73) | HTR3A | |
| Iodide SCHEMBL7626107 | 0.83 | HTR3A (0.57) | HTR3A | |
| SCHEMBL7621226 | 0.83 | HTR3A (0.63) | HTR3A | |
| Emedastine SCHEMBL29770 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079545-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KANEBO, LTD. (JP) | 1986-05-21 | — | — | EP | claimed |
| US-4430343-A | ANTIHISTAMINES | KANEBO, LTD. (JP) | 1984-02-07 | — | — | US | claimed |
| EP-0079545-A1 | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1983-05-25 | — | — | EP | claimed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| EP-0468884-B1 | Benzimidazole derivatives, their preparation and their application as medicaments | ESTEVE LABOR DR (ES) | 1995-12-20 | — | — | EP | disclosed |
| US-5182280-A | DERIVATIVES OF BENZIMIDAZOLE AND THEIR USE AS ANTIHISTAMINES | LABORATORIOS DEL DR. ESTEVE, S. A. (ES) | 1993-01-26 | — | — | US | disclosed |
| EP-0468884-A1 | Benzimidazole derivatives, their preparation and their application as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-01-29 | — | — | EP | disclosed |
| EP-0079545-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KANEBO, LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |
| US-4430343-A | ANTIHISTAMINES | KANEBO, LTD. (JP) | 1984-02-07 | — | — | US | disclosed |
| EP-0079545-A1 | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1983-05-25 | — | — | EP | disclosed |