Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9212923 | 0.94 | CYP3A4 (0.33) | MAP3K14CYP3A4CYP2C9RORCTHRB | |
| Sulfuric Acid SCHEMBL9216691 | 0.92 | MAP3K14 (0.36) | MAP3K14CYP3A4CYP2C9RORCTHRB | |
| SCHEMBL28318484 | 0.86 | CYP3A4 (0.39) | MAP3K14CYP3A4CYP2C9THRBSLC6A4 | |
| SCHEMBL9835917 | 0.78 | SLC6A4 (0.41) | MAP3K14CYP3A4CYP2C9THRBSLC6A4 | |
| SCHEMBL9664109 | 0.73 | CYP3A4 (0.38) | MAP3K14CYP3A4CYP2C9THRBSLC6A4 | |
| SCHEMBL9835436 | 0.72 | SLC6A4 (0.43) | MAP3K14CYP3A4CYP2C9THRBSLC6A4 | |
| SCHEMBL9662300 | 0.71 | CYP3A4 (0.39) | MAP3K14CYP3A4CYP2C9THRBSLC6A4 | |
| SCHEMBL10885411 | 0.68 | SLC6A4 (0.44) | MAP3K14CYP3A4CYP2C9THRBSLC6A4 | |
| SCHEMBL8804298 | 0.67 | CYP3A4 (0.43) | MAP3K14CYP3A4CYP2C9THRBSLC6A4 | |
| SCHEMBL10512062 | 0.67 | CYP3A4 (0.64) | CYP3A4CYP2C9THRBSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636120-A1 | EPOXIDATION PROCESS OF CARBONYL COMPOUNDS USING SULPHONIUM OR SULPHOXONIUM YLIDES AND INTERMEDIATES | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1992014703-A1 | EPOXIDATION PROCESS OF CARBONYL COMPOUNDS USING SULPHONIUM OR SULPHOXONIUM YLIDES AND INTERMEDIATES | ZENECA LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |