Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210514 | 1.00 | TSHR (0.35) | TSHRTHRBSIGMAR1SIRT2CNR1 | |
| SCHEMBL9205986 | 1.00 | TSHR (0.35) | TSHRTHRBSIGMAR1SIRT2CNR1 | |
| SCHEMBL9211324 | 1.00 | TSHR (0.35) | TSHRTHRBSIGMAR1SIRT2CNR1 | |
| SCHEMBL9212119 | 1.00 | TSHR (0.35) | TSHRTHRBSIGMAR1SIRT2CNR1 | |
| SCHEMBL9205568 | 1.00 | TSHR (0.35) | TSHRTHRBSIGMAR1SIRT2CNR1 | |
| SCHEMBL9207711 | 0.96 | TSHR (0.35) | TSHRTHRBSIGMAR1SIRT2EPHX1 | |
| SCHEMBL9210725 | 0.96 | TSHR (0.35) | TSHRTHRBSIGMAR1SIRT2EPHX1 | |
| SCHEMBL9207596 | 0.89 | FAAH (0.41) | PTPN1 | |
| SCHEMBL9202783 | 0.88 | FAAH (0.40) | PTPN1 | |
| SCHEMBL9202788 | 0.88 | FAAH (0.40) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |