Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216469 | 0.77 | ABCB1 (0.44) | ABCB1SIRT2SIRT1EGLN2 | |
| SCHEMBL7269294 | 0.70 | CA12 (0.39) | ABCB1PTGS2P2RY6 | |
| SCHEMBL6615734 | 0.70 | EGLN2 (0.44) | ABCB1SIRT2SIRT1EGLN2 | |
| SCHEMBL9213153 | 0.69 | ABCB1 (0.52) | ABCB1SIRT2SIRT1 | |
| SCHEMBL9147949 | 0.68 | PTGS2 (0.42) | ABCB1PTGS2ADRA2ADRD5P2RY6 | |
| SCHEMBL959690 | 0.68 | EGLN2 (0.55) | EGLN2 | |
| SCHEMBL14738332 | 0.68 | EGLN2 (0.45) | EGLN2 | |
| SCHEMBL29945049 | 0.68 | EGLN2 (0.45) | EGLN2 | |
| SCHEMBL15057350 | 0.68 | EGLN2 (0.50) | EGLN2 | |
| SCHEMBL30381517 | 0.67 | AAK1 (0.41) | ABCB1SIRT2SIRT1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | claimed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | disclosed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |