Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213622 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9209108 | 0.86 | ACAT1 (0.57) | — | |
| SCHEMBL9208497 | 0.86 | ACAT1 (0.54) | — | |
| SCHEMBL9210502 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9211240 | 0.85 | ACAT1 (0.59) | — | |
| SCHEMBL9213144 | 0.85 | ACAT1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL9212101 | 0.85 | ACAT1 (0.53) | KDM4E | |
| SCHEMBL9668750 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9214196 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9212595 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505468-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS ACYL COENZYME-A INHIBITORS | RHONE POULENC SANTE (FR) | 1995-04-26 | — | — | EP | claimed |
| EP-0505468-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS ACYL COENZYME-A INHIBITORS | RHONE POULENC SANTE (FR) | 1995-04-26 | — | — | EP | disclosed |
| WO-1991009021-A1 | IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-06-27 | — | — | WO | disclosed |