Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.37 |
| ▸ | FDPS | P14324 | 9/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848911 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL8854153 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL8854171 | 0.97 | TSHR (0.35) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL21370739 | 0.90 | TSHR (0.33) | TSHRTHRBFDPS | |
| SCHEMBL9209416 | 0.88 | FAAH (0.45) | — | |
| Phosphoric Acid SCHEMBL28595612 | 0.88 | GGPS1 (0.52) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL9214931 | 0.88 | FAAH (0.45) | — | |
| SCHEMBL9210731 | 0.88 | FAAH (0.45) | — | |
| SCHEMBL9203676 | 0.88 | FAAH (0.45) | — | |
| SCHEMBL9206205 | 0.83 | FAAH (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |