Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964432 | 0.81 | NPSR1 (0.41) | MAPTLMNARAB9ASLC6A2SLC6A3 | |
| SCHEMBL7964429 | 0.81 | NPSR1 (0.41) | MAPTLMNARAB9ASLC6A2SLC6A3 | |
| SCHEMBL7963035 | 0.74 | NPSR1 (0.37) | POLBMEN1KMT2AMAPTHTT | |
| SCHEMBL7963034 | 0.74 | NPSR1 (0.37) | POLBMEN1KMT2AMAPTHTT | |
| SCHEMBL8304389 | 0.71 | TP53 (0.33) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL7762961 | 0.62 | NPSR1 (0.39) | KMT2AMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL7967762 | 0.62 | NPSR1 (0.39) | KMT2AMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL7933665 | 0.60 | DGAT1 (0.48) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL7933664 | 0.60 | DGAT1 (0.48) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL8447906 | 0.60 | MEN1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637298-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF Aktiengesellschaft (DE) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022280-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |