Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213303 | 0.94 | MEN1 (0.49) | ABCB1HTR1ASLC6A4DHCR7MEN1 | |
| Hydrochloric Acid SCHEMBL9216467 | 0.85 | DHCR7 (0.58) | ABCB1HTR1ASLC6A4DHCR7KMT2A | |
| Hydrochloric Acid SCHEMBL9215875 | 0.84 | ABCB1 (0.54) | ABCB1HTR1ASLC6A4DHCR7 | |
| SCHEMBL9211025 | 0.83 | HRH3 (0.49) | ABCB1HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL9215240 | 0.83 | MEN1 (0.47) | ABCB1HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL9207036 | 0.82 | HRH3 (0.50) | ABCB1HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL9211782 | 0.81 | DHCR7 (0.51) | ABCB1DHCR7 | |
| SCHEMBL9205910 | 0.81 | DHCR7 (0.57) | ABCB1DHCR7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9215735 | 0.80 | ABCB1 (0.57) | ABCB1SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9206759 | 0.80 | DHCR7 (0.64) | ABCB1HTR1ASLC6A4DHCR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |