Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284694 | 0.86 | ADORA2A (0.52) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL83136 | 0.83 | ADORA2A (0.53) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL16424117 | 0.82 | ADORA2A (0.57) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL5013717 | 0.82 | ADORA2A (0.52) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL431678 | 0.82 | MEN1 (0.53) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL3256179 | 0.82 | AURKA (0.53) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL2605008 | 0.79 | KEAP1 (0.51) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL18242705 | 0.79 | ELANE (0.53) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL6711781 | 0.79 | ADORA2A (0.48) | ADORA2AMEN1KMT2ACDC25BALDH1A1 | |
| SCHEMBL2316204 | 0.79 | MEN1 (0.54) | ADORA2AMEN1KMT2ACDC25BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450461-B1 | LHRH Analogs | UNIV TULANE (US) | 1995-09-06 | — | — | EP | disclosed |