SCHEMBL9214020

SCHEMBL9214020

CCOC(C)CN(C(=O)CCl)c1c(C)cccc1CC

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 7/20 0.65
ALDH1A1 P00352 6/20 0.65
TDP1 Q9NUW8 3/20 0.65
CYP3A4 P08684 1/20 0.65
NR1I2 O75469 1/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 1/20 0.35
NPC1 O15118 1/20 0.35
GPX4 P36969 1/20 0.35
RAB9A P51151 1/20 0.35
PAX8 Q06710 1/20 0.35
FFAR1 O14842 1/20 0.35
RORC P51449 1/20 0.35
LMNA P02545 1/20 0.34
NLRP3 Q96P20 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3467788 0.90 TP53 (0.65) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL16394235 0.87 TP53 (0.67) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL65705 0.84 TP53 (0.74) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL29349823 0.84 TP53 (0.74) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL10428571 0.82 TP53 (0.66) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL9207005 0.81 TP53 (0.64) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL10858355 0.81 TP53 (0.74) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL9213147 0.80 ALDH1A1 (0.54) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL9211212 0.80 ALDH1A1 (0.51) TP53ALDH1A1TDP1CYP3A4NR1I2
SCHEMBL27564754 0.80 TP53 (0.61) TP53ALDH1A1TDP1CYP3A4NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US claimed
EP-0397602-A1 N-phenylpyrrolidines CIBA-GEIGY AG (CH) 1990-11-14 EP claimed
EP-0357557-A2 Synergistic mixture CIBA-GEIGY AG (CH) 1990-03-07 EP claimed
EP-0378508-B1 Antidotes to modify the resistance of cultivated plants to agrochemical agents CIBA GEIGY AG (CH) 1995-03-01 EP disclosed
US-5215570-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed
US-5175289-A Antidotes for protecting cultivated plants from the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1992-12-29 US disclosed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US disclosed
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5041157-A Protecting soybeans or cereals CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5032169-A Antidotes for herbicides CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-5028256-A Metolachlor and an acylamide compound, for maize or sorghum CIBA-GEIGY CORPORATION (US) 1991-07-02 US disclosed
US-4601745-A Composition for the protection of cultivated plants against the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1986-07-22 US disclosed
US-4576628-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-03-18 US disclosed
EP-0092517-B1 OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THESE COMPOUNDS AND THEIR USE CIBA-GEIGY AG (CH) 1986-03-12 EP disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
EP-0094348-B1 OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THE OXIME ETHERS AND THEIR USE CIBA-GEIGY AG (CH) 1985-07-24 EP disclosed
US-4530716-A Plant safening agent CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
US-4523947-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed
EP-0089313-B1 OXIME ETHERS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THE OXIME ETHERS AND THEIR USE CIBA-GEIGY AG (CH) 1985-05-02 EP disclosed