Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 3/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8741078 | 0.99 | ALDH1A1 (0.66) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6210119 | 0.94 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9522683 | 0.89 | ALDH1A1 (0.71) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9214162 | 0.89 | ALDH1A1 (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL6215429 | 0.88 | ALDH1A1 (0.52) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL680228 | 0.86 | ALDH1A1 (0.57) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9570692 | 0.86 | ALDH1A1 (0.57) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8982806 | 0.86 | ALDH1A1 (0.57) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6211468 | 0.86 | ALDH1A1 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9671640 | 0.86 | ALDH1A1 (0.72) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2292288-A | — | — | None | — | — | JP | disclosed |
| EP-0393424-B1 | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | BAYER AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| US-5241076-A | 1,4-diazatricyclo [6.3.0.0]undecanes | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| US-5177210-A | Preparation of 2,7-diazabicyclo(3.3.0)octanes | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-05 | — | — | US | disclosed |
| US-5071999-A | Preparation of 2,7-diazabicyclo[3.3.0]octanes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| JP-H02292288-A | 2,7-DIAZABICYCLO(3.3.0)OCTANE | BAYER AG | 1990-12-03 | — | — | JP | disclosed |