Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 6/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399914 | 0.87 | CYP1A1 (0.33) | — | |
| SCHEMBL10699981 | 0.86 | — | — | |
| SCHEMBL10700056 | 0.85 | — | — | |
| SCHEMBL9210040 | 0.84 | GABRP (0.36) | NPC1RAB9ADRD2 | |
| SCHEMBL9203586 | 0.84 | — | — | |
| SCHEMBL10697119 | 0.84 | — | — | |
| SCHEMBL9211633 | 0.83 | FFAR1 (0.35) | NPC1HTTRAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL10697942 | 0.83 | — | — | |
| SCHEMBL9214601 | 0.83 | HRH3 (0.35) | — | |
| SCHEMBL9213738 | 0.83 | GABRP (0.34) | MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216624-B1 | Pesticidal compounds | ROUSSEL UCLAF (FR) | 1995-02-22 | — | — | EP | disclosed |
| US-5371075-A | Pesticides | ROUSSEL-UCLAF (FR) | 1994-12-06 | — | — | US | disclosed |
| US-5057508-A | Bicyclo(2-2-1)octanes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-10-15 | — | — | US | disclosed |
| US-4965257-A | INSECTICIDES, ACARICIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0216624-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-04-01 | — | — | EP | disclosed |