Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209218 | 1.00 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL27847425 | 1.00 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL3468028 | 0.83 | NPC1 (0.53) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL5451636 | 0.82 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL9220106 | 0.82 | ABCB1 (0.46) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL9216460 | 0.82 | ABCB1 (0.46) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL29254207 | 0.81 | CRHBP (0.46) | ALDH1A1SMN1; SMN2LMNACYP2C19TSHR | |
| SCHEMBL29254204 | 0.81 | CRHBP (0.46) | ALDH1A1SMN1; SMN2LMNACYP2C19TSHR | |
| SCHEMBL2902849 | 0.78 | NPC1 (0.62) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL25181454 | 0.76 | TDP1 (0.46) | NPC1RAB9AKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324707-A | Synthesis method of (S) -6-hydroxymethyl-morpholin-3-one | 西安宇特邦医药科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118324707-A | Synthesis method of (S) -6-hydroxymethyl-morpholin-3-one | 西安宇特邦医药科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |