Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.77 |
| ▸ | CA9 | Q16790 | 10/20 | 0.77 |
| ▸ | CA1 | P00915 | 9/20 | 0.77 |
| ▸ | CA6 | P23280 | 5/20 | 0.77 |
| ▸ | CA7 | P43166 | 5/20 | 0.77 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.77 |
| ▸ | CA4 | P22748 | 5/20 | 0.77 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.77 |
| ▸ | CA2 | P00918 | 3/20 | 0.77 |
| ▸ | CA3 | P07451 | 3/20 | 0.77 |
| ▸ | CA5A | P35218 | 3/20 | 0.72 |
| ▸ | MAOB | P27338 | 8/20 | 0.69 |
| ▸ | MAOA | P21397 | 7/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045405 | 0.90 | CA12 (0.82) | CA12CA9CA1CA6CA7 | |
| SCHEMBL12304245 | 0.90 | CA12 (0.81) | CA12CA9CA1CA6CA7 | |
| SCHEMBL15941352 | 0.88 | CA12 (0.65) | CA12CA9CA1CA6CA7 | |
| 7-Butoxycoumarin SCHEMBL6686295 | 0.87 | CA12 (1.00) | CA12CA9CA1CA6CA7 | |
| SCHEMBL31086623 | 0.87 | CA12 (0.77) | CA12CA9CA1CA6CA7 | |
| SCHEMBL31086804 | 0.87 | CA12 (0.77) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7883068 | 0.86 | CA12 (0.75) | CA12CA9CA1CA6CA7 | |
| SCHEMBL11946742 | 0.86 | CA12 (0.85) | CA12CA9CA1CA6CA7 | |
| SCHEMBL28590898 | 0.84 | CA12 (0.73) | CA12CA9CA1CA6CA7 | |
| SCHEMBL29133437 | 0.84 | CA12 (0.73) | CA12CA9CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | disclosed |
| US-5189171-A | Antipsychotic benzodioxan derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0520674-A1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5166367-A | Anxiolytic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0175541-B1 | AMINOALKOXYBENZOPYRANONES AND PROCESSES FOR THE PRODUCTION THEREOF | WARNER-LAMBERT COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |
| US-4701456-A | SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |
| EP-0175541-A1 | Aminoalkoxybenzopyranones and processes for the production thereof | WARNER-LAMBERT COMPANY (US) | 1986-03-26 | — | — | EP | disclosed |