Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | OGA | O60502 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220710 | 0.92 | HRH3 (0.45) | HRH3MAPTOGASMOGPR84 | |
| SCHEMBL9219478 | 0.83 | HRH3 (0.47) | HRH3MAPTOGASMOENPP1 | |
| SCHEMBL15548336 | 0.77 | HRH3 (0.54) | HRH3OGASMOKMT2AEPHX2 | |
| SCHEMBL21626550 | 0.77 | HRH3 (0.52) | HRH3MAPTOGASMOKMT2A | |
| SCHEMBL31514107 | 0.74 | HRH3 (0.48) | HRH3MAPTOGAKMT2AEPHX2 | |
| SCHEMBL4890873 | 0.74 | LMNA (0.55) | HRH3MAPTOGASMOKMT2A | |
| SCHEMBL9200711 | 0.72 | LMNA (0.56) | MAPTKMT2A | |
| SCHEMBL1562360 | 0.72 | MAPT (0.43) | MAPTOGAKMT2A | |
| SCHEMBL3635646 | 0.72 | BPTF (0.47) | HRH3OGA | |
| SCHEMBL10072964 | 0.70 | OGA (0.50) | HRH3OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320032-B1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1995-01-18 | — | — | EP | disclosed |
| US-5231184-A | Viricide intermediate | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-27 | — | — | US | disclosed |
| CN-1021328-C | PROCESS FOR PREPARING PYRIDAZINAMINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1993-06-23 | — | — | CN | disclosed |
| US-5106973-A | Viricide intermediates | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-21 | — | — | US | disclosed |
| US-4992433-A | Viricides | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-12 | — | — | US | disclosed |
| EP-0320032-A1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-06-14 | — | — | EP | disclosed |
| CN-1033274-A | The preparation method of new Pyridazinyl amine derivative | JANSSEN PHARMACEUTICA NV (BE) | 1989-06-07 | — | — | CN | disclosed |