Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833694 | 1.00 | ALDH1A1 (0.32) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL8832676 | 0.93 | CYP19A1 (0.31) | — | |
| SCHEMBL9215975 | 0.93 | CYP19A1 (0.31) | — | |
| SCHEMBL8833434 | 0.90 | CYP19A1 (0.31) | — | |
| SCHEMBL8834378 | 0.88 | CYP19A1 (0.31) | — | |
| SCHEMBL9221341 | 0.88 | CYP19A1 (0.31) | — | |
| SCHEMBL8833524 | 0.86 | — | — | |
| SCHEMBL9026904 | 0.85 | CYP19A1 (0.32) | — | |
| SCHEMBL9026899 | 0.85 | CYP19A1 (0.32) | — | |
| SCHEMBL9026747 | 0.85 | CYP19A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |