Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GGT1 | P19440 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215156 | 1.00 | KDM4E (0.73) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| Sorbic Acid SCHEMBL8598635 | 0.96 | KDM4E (0.67) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7712909 | 0.89 | KDM4E (0.80) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7712911 | 0.89 | KDM4E (0.80) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| Bissalicyl Fumarate SCHEMBL13351990 | 0.85 | KDM4E (1.00) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL9390691 | 0.81 | TSHR (0.53) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL9390684 | 0.81 | TSHR (0.53) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL21710510 | 0.81 | KDM4E (0.83) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL4364436 | 0.80 | MAOB (0.48) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL27149 | 0.80 | MAOB (0.48) | KDM4EHSD17B10HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681582-A1 | PYRAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |