Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CSK | P41240 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220456 | 0.82 | IDO1 (0.37) | FYNALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9213441 | 0.79 | EGLN2 (0.40) | CDK2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9215058 | 0.79 | GPR119 (0.40) | CDK2ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9222573 | 0.77 | PRKD3 (0.41) | PRKD3PRKD1PRKD2HTTMAPT | |
| SCHEMBL9221980 | 0.77 | KDM1A (0.36) | SRCCYP11B2HTTMAPTALDH1A1 | |
| SCHEMBL9215295 | 0.76 | PIM1 (0.48) | ABL1SRCALDH1A1KDM4ELMNA | |
| SCHEMBL9222715 | 0.74 | NPC1 (0.40) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9218780 | 0.73 | PIK3CD (0.43) | FYNCYP11B2 | |
| SCHEMBL9215756 | 0.71 | SRC (0.45) | RIPK2ABL1SRCMAPTALDH1A1 | |
| SCHEMBL9219234 | 0.70 | NPC1 (0.57) | ABL1FYNSRCCDK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269859-B2 | Pyrazolotriazine compounds | OTSUKA PHARMA CO LTD (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0269859-A2 | Pyrazolotriazine compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |