Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191598 | 0.79 | — | — | |
| SCHEMBL2244618 | 0.75 | — | — | |
| SCHEMBL656544 | 0.74 | — | — | |
| SCHEMBL8670495 | 0.73 | ALOX5 (0.43) | ALOX5SLC1A3SLC1A2SLC1A1NAAA | |
| SCHEMBL11576084 | 0.73 | CYP1A2 (1.00) | CYP1A2CYP2D6CYP2C19CYP2A6HTR2A | |
| Hydrochloric Acid SCHEMBL9257543 | 0.72 | — | — | |
| Oxalic Acid SCHEMBL7504861 | 0.69 | ALOX5 (0.47) | CYP2D6CYP2C19ALOX5CYP2A6HTR2A | |
| SCHEMBL12796854 | 0.68 | CYP1A2 (0.67) | CYP1A2CYP2D6CYP2C19SMN1; SMN2LOXL2 | |
| SCHEMBL9219651 | 0.67 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL9220089 | 0.67 | ALOX5 (0.38) | CYP1A2CYP2D6ALOX5SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492178-B1 | Naphthoic acid derivative | FUJIREBIO KK (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5324728-A | Lipoxygenase inhibiting antiallergens | FUJIREBIO INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0492178-A2 | Naphthoic acid derivative | FUJIREBIO INC. (JP) | 1992-07-01 | — | — | EP | disclosed |