Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | DTYMK | P23919 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395903 | 0.87 | TSHR (0.62) | POLBTSHRCYP3A4ALDH1A1DTYMK | |
| SCHEMBL149316 | 0.86 | DTYMK (0.62) | POLBMEN1KMT2AKDM4ETSHR | |
| SCHEMBL29935450 | 0.86 | DTYMK (0.62) | POLBMEN1KMT2AKDM4ETSHR | |
| SCHEMBL27480722 | 0.85 | ALDH1A1 (0.56) | POLBMEN1KMT2ATSHRCYP3A4 | |
| Phthalic Acid SCHEMBL10580388 | 0.85 | TSHR (0.59) | POLBMEN1KMT2ACDC25BKDM4E | |
| SCHEMBL8446509 | 0.84 | DTYMK (0.60) | POLBMEN1KMT2AKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL3730916 | 0.84 | DTYMK (0.60) | POLBMEN1KMT2AKDM4ETSHR | |
| SCHEMBL11048087 | 0.84 | DTYMK (0.60) | POLBMEN1KMT2AKDM4ETSHR | |
| Potassium Ion SCHEMBL11048083 | 0.84 | DTYMK (0.60) | POLBMEN1KMT2AKDM4ETSHR | |
| SCHEMBL5705801 | 0.82 | TSHR (0.59) | POLBMEN1KMT2ACDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569457-B1 | USE OF THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO- [2,3-A]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1995-06-14 | — | — | EP | disclosed |