Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9211557 | 0.99 | HRH3 (0.47) | HRH3KDM4EALDH1A1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL9213581 | 0.92 | KDM4E (0.46) | HRH3KDM4EALDH1A1DRD2 | |
| SCHEMBL9739297 | 0.91 | HRH3 (0.48) | HRH3KDM4EALDH1A1KMT2AEDNRA | |
| Hydrochloric Acid SCHEMBL9215867 | 0.90 | KDM4E (0.47) | HRH3KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL9207471 | 0.90 | DRD2 (0.43) | HRH3DRD2 | |
| Hydrochloric Acid SCHEMBL9214294 | 0.89 | DRD2 (0.43) | DRD2 | |
| SCHEMBL9207830 | 0.89 | HRH3 (0.51) | HRH3KDM4EALDH1A1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL9213538 | 0.88 | HRH3 (0.50) | HRH3KDM4EALDH1A1KMT2ADRD2 | |
| SCHEMBL9217118 | 0.87 | DRD2 (0.49) | HRH3KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL9213457 | 0.86 | DRD2 (0.47) | HRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |