Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | USP2 | O75604 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | BLM | P54132 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.58 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907358 | 0.83 | CYP19A1 (0.59) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL11806000 | 0.81 | CYP19A1 (0.62) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL11046399 | 0.80 | CYP19A1 (0.57) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL1478995 | 0.80 | CYP19A1 (0.57) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL30439813 | 0.79 | MEN1 (0.81) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL497032 | 0.79 | MEN1 (0.81) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL10940569 | 0.79 | CYP19A1 (0.64) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL17207499 | 0.78 | CYP19A1 (0.68) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL14882566 | 0.78 | CYP19A1 (0.68) | CYP19A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL11517791 | 0.78 | CYP19A1 (0.68) | CYP19A1MEN1KMT2AMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295316-B1 | Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones | AMERICAN CYANAMID CO (US) | 1995-11-08 | — | — | EP | disclosed |