SCHEMBL497032

SCHEMBL497032

O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCO)ccc(NCCO)c21

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.81
KMT2A Q03164 6/20 0.81
MAPK1 P28482 4/20 0.81
TDP1 Q9NUW8 4/20 0.81
LMNA P02545 3/20 0.81
BLM P54132 3/20 0.81
USP2 O75604 3/20 0.81
TP53 P04637 3/20 0.81
RECQL P46063 3/20 0.81
NPC1 O15118 3/20 0.81
RAB9A P51151 3/20 0.81
NSD2 O96028 3/20 0.81
CSNK2A2 P19784 3/20 0.81
CSNK2B P67870 3/20 0.81
CSNK2A1 P68400 3/20 0.81
CSNK2A3 Q8NEV1 3/20 0.81
SMN1; SMN2 Q16637 2/20 0.81
MTOR P42345 2/20 0.81
TOP2A P11388 2/20 0.81
CYP3A4 P08684 2/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30439813 1.00 MEN1 (0.81) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL11041207 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
Mitoxantrone SCHEMBL29353270 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
Mitoxantrone SCHEMBL29720597 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL11036806 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL11391594 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
Mitoxantrone SCHEMBL20214110 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL11517949 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
Mitoxantrone SCHEMBL3000 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA
SCHEMBL11038495 0.90 MEN1 (1.00) MEN1KMT2AMAPK1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0843994-B1 Composition and process for dyeing hair WELLA AG (DE) 2003-08-06 EP claimed
EP-0843993-B1 Composition and process for dyeing hair WELLA AG (DE) 2003-08-06 EP claimed
US-5965114-A DYE CONTAINING MASS OF COSMETIC CARRIER AND 5-BROMO-4-CHLORO-3-INDOLYL-B-D-GALACTOSIDE; READY-TO-USE DYE IS OBTAINED BY MIXING THE DYE CONTAINING MASS WITH A HYDROLASE ENZYME; EASILY CONVERTED INDIGO DYE PRECURSOR WELLA AG (DE) 1999-10-12 US claimed
US-20230384498-A1 OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
US-20230384498-A1 OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
US-20230358935-A1 OPTICAL FILM AND ELECTROLUMINESCENCE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-09 US disclosed
US-20230358935-A1 OPTICAL FILM AND ELECTROLUMINESCENCE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-09 US disclosed
US-20230332048-A1 LIGHT ABSORPTION ANISOTROPIC FILM, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-10-19 US disclosed
US-20230332048-A1 LIGHT ABSORPTION ANISOTROPIC FILM, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-10-19 US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
EP-0898954-A2 Composition for dyeing keratin fibres Wella Aktiengesellschaft (DE) 1999-03-03 EP disclosed
US-5865855-A COUPLING TWO PYRAZOLE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 US disclosed
EP-0867171-A2 Powder composition for the preparation of gels comprising a methyl hydroxyalkyl cellulose Wella Aktiengesellschaft (DE) 1998-09-30 EP disclosed
EP-0782845-A1 Hair colorant and hair colorant slurry for dyeing human hair HANS SCHWARZKOPF GmbH (DE) 1997-07-09 EP disclosed
EP-0605566-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN CHEMICAL COMPANY (US) 1994-07-13 EP disclosed
WO-1993006147-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-04-01 WO disclosed
US-5194463-A LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-03-16 US disclosed
US-4886517-A GOOD WATER SOLUBILITY L'OREAL (FR) 1989-12-12 US disclosed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 MEN1 2794/4885KMT2A 2181/4885MAPK1 2053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.