Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 9/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211417 | 0.80 | PDK1 (0.54) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL26485577 | 0.72 | POLB (0.50) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9220138 | 0.71 | POLB (0.44) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9207643 | 0.70 | POLB (0.40) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL2756164 | 0.70 | POLB (0.58) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL15920638 | 0.68 | POLB (0.59) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL1272703 | 0.67 | POLB (0.48) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL2179891 | 0.67 | UBE2T (0.55) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL2175795 | 0.67 | PDK1 (0.53) | PDK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL14421725 | 0.67 | PDK1 (0.53) | PDK1POLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |