Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN4 | Q9Y3Q4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207879 | 0.96 | KMT2A (0.33) | HCN4MAPTCYP3A4ALOX15KDM4E | |
| SCHEMBL9204857 | 0.91 | ADRA1B (0.40) | KDM4EHTR1ADRD3SMN1; SMN2ADRA1B | |
| Hydrochloric Acid SCHEMBL9215535 | 0.91 | ADRA1B (0.40) | KDM4ESMN1; SMN2MEN1KMT2AADRA1B | |
| SCHEMBL9208157 | 0.89 | MEN1 (0.37) | MAPTKDM4ETSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9213751 | 0.87 | KDM4E (0.36) | MAPTKDM4ETSHRSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9206175 | 0.86 | PDE4B (0.40) | MAPTKDM4ETSHRDRD3MEN1 | |
| SCHEMBL9212598 | 0.86 | PRMT5 (0.35) | MAPTKDM4ETSHRSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9213973 | 0.86 | ADRA1B (0.34) | MAPTKDM4ETSHRSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9204551 | 0.86 | ADRA1B (0.41) | KDM4ESMN1; SMN2ADRA1BPRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL9204657 | 0.85 | PRMT5 (0.35) | MAPTKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |