Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218602 | 0.83 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL9028144 | 0.81 | ECE1 (0.34) | ECE1CYP19A1PARP1CHRM1 | |
| SCHEMBL9221004 | 0.80 | ECE1 (0.34) | ECE1CYP19A1PARP1CHRM1 | |
| SCHEMBL9027688 | 0.80 | ECE1 (0.34) | ECE1CYP19A1PARP1CHRM1 | |
| SCHEMBL8833004 | 0.79 | ECE1 (0.33) | ECE1CHRM1 | |
| SCHEMBL8833000 | 0.79 | ECE1 (0.33) | ECE1CHRM1 | |
| SCHEMBL9212162 | 0.79 | ECE1 (0.33) | ECE1CHRM1 | |
| SCHEMBL8833028 | 0.79 | ECE1 (0.34) | ECE1CHRM1 | |
| SCHEMBL9543274 | 0.79 | ECE1 (0.34) | ECE1CHRM1 | |
| SCHEMBL9028139 | 0.75 | ECE1 (0.34) | ECE1CYP19A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |