SCHEMBL9218602

SCHEMBL9218602

C=CCOC(=O)N1CC(O)CC1CCc1ncc(C=CC(N)=O)[nH]1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215968 0.83 ECE1 (0.33) CYP19A1
SCHEMBL9026391 0.77 CYP19A1 (0.33) CYP19A1
SCHEMBL9542928 0.75
SCHEMBL8832516 0.75
SCHEMBL9542123 0.75
SCHEMBL9542929 0.75
SCHEMBL9220817 0.72 CYP19A1 (0.35) CYP19A1
SCHEMBL9216047 0.71 TBXAS1 (0.37) CYP19A1
SCHEMBL9027186 0.71 CYP19A1 (0.33) CYP19A1
SCHEMBL8833539 0.69 SIGMAR1 (0.33) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0636133-A1 SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-02-01 EP disclosed