Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 6/20 | 0.71 |
| ▸ | HTT | P42858 | 5/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.68 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MPL | P40238 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205554 | 0.89 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL4959508 | 0.82 | MPL (0.74) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL5425167 | 0.73 | KDM4E (0.55) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL5425163 | 0.73 | NPY5R (0.59) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL5466354 | 0.71 | HDAC6 (0.54) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL9206837 | 0.71 | KDM4E (1.00) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| Iodide SCHEMBL4960911 | 0.70 | KDM4E (0.97) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL2381383 | 0.69 | MAPT (0.56) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL2381391 | 0.69 | KDM4E (0.55) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL5394051 | 0.68 | NPY5R (0.57) | ALDH1A1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284018-B1 | Benzopyran[4,3-d]-thiazole-derivatives with anti-allergic, anti-anaphylactic and anti-arthritic activity and compositions containing them | ZAMBON SPA (IT) | 1995-08-02 | — | — | EP | disclosed |
| US-4829077-A | Benzopyran[4,3-d]-thiazole-derivatives with anti-allergic, anti-anaphylactic and anti-arithritic activity and compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1989-05-09 | — | — | US | disclosed |
| EP-0284018-A2 | Benzopyran[4,3-d]-thiazole-derivatives with anti-allergic, anti-anaphylactic and anti-arthritic activity and compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1988-09-28 | — | — | EP | disclosed |