Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501648 | 1.00 | GAA (0.42) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9501932 | 0.91 | GAA (0.46) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9218040 | 0.91 | GAA (0.46) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9501521 | 0.86 | MAPT (0.40) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9218454 | 0.86 | MAPT (0.40) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9500764 | 0.84 | GAA (0.38) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9215872 | 0.84 | GAA (0.38) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9216623 | 0.80 | GAA (0.38) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9501617 | 0.80 | GAA (0.38) | GAAMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9217450 | 0.77 | ALDH1A1 (0.39) | GAAMAPTALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412849-B1 | Azole pesticides | AGREVO UK LTD (GB) | 1995-12-20 | — | — | EP | disclosed |
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |